Wine Information Council
27 june 2009
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Modification of the association between alcohol drinking and non-HDL cholesterol by gender

BACKGROUND: Serum non-HDL cholesterol is a strong predictor of cardiovascular diseases. We studied the relationship between habitual alcohol drinking and non-HDL cholesterol. METHODS: Healthy male subjects (n = 27,005) and female subjects (n = 16,805) were divided into 5 groups by average daily ethanol intake. Serum non-HDL cholesterol level and prevalence of serum high non-HDL cholesterol (> or = 170 mg/dl) were compared among the groups. RESULTS: Non-HDL cholesterol level and prevalence of high non-HDL cholesterol became lower as alcohol intake increased. The threshold alcohol intake in the drinker groups showing significantly lower non-HDL cholesterol level and significantly lower prevalence of high non-HDL cholesterol, compared with those in non-drinkers, was lower in women (<10 g/d) than in men (> or = 10 and <20 g/d). Odds ratios of each drinker group vs. the non-drinker group for high non-HDL cholesterol became lower as alcohol intake increased. The odds ratio of each drinker group vs. the non-drinker group for high non-HDL cholesterol tended to be lower in women than in men. CONCLUSIONS: The results suggest that even light drinking is sufficient to significantly lower serum non-HDL cholesterol and that this effect of alcohol drinking on non-HDL cholesterol is more pronounced in women than in men

Additional Info

  • Authors

    Wakabayashi I.; Groschner K.

  • Issue

    Clin.Chim.Acta / pages 154-159 / volume 404

  • Published Date

    27 june 2009

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