Alcohol Consumption and Risk of Incident Frailty: The English Longitudinal Study of Aging
BACKGROUND: Alcohol consumption is a common modifiable lifestyle factor. Alcohol may be a risk factor for frailty, however, there is limited evidence in the literature.
OBJECTIVE: The objectives of this study were to examine the association of alcohol consumption with the risk of incident frailty.
METHODS: This is a prospective panel study of 2544 community-dwelling people aged 60 years and older in England. FrailtyFrailty is a clinical syndrome characterized by an age-related decline of multiple physiological fun... status defined by frailty phenotype criteria was measured at baseline and 4 years later. Participants free of frailty at baseline were divided into 5 groups based on quantity of self-reported alcohol consumption per week with cut-points at 0, 7, 14, and 21 UK units per week. Adjusted odds ratios (OR) were calculated for incident frailty according to the alcohol consumption using logistic regression models.
RESULTS: Compared with the low consumption group (>0 and 21 units per week) had a significantly lower incident frailty risk (unadjusted OR 0.45, 95% CI 0.270.75, P < .01), which became nonsignificant on adjustment for sociodemographic factors (OR 0.64, 95% CI 0.371.13, P = .12).
CONCLUSIONS/IMPLICATIONS: We found that nondrinkers were more likely than those with low alcohol consumption to develop frailty, but this appeared to be explained by poorer baseline health status. No evidence was found for an association between high levels of alcohol consumption and becoming frail. Future studies with information on life-course history of alcohol use, especially for those classified as nondrinkers in old age, are warranted.
Additional Info
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Authors
Kojima G.; Jivraj S.; Iliffe S.; Falcaro M.; Liljas A.; Walters K. -
Issue
J Am Med Dir Assoc. 2019 Jun;20(6):725-729. doi: 10.1016/j.jamda.2018.10.011. -
Published Date
20 june 2019
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